Dr. Karin Knešaurek is a nuclear medicine physicist and Professor of Radiology at the Icahn School of Medicine at Mount Sinai, New York, USA. His general areas of interest and research are; PET/MRI, PET/CT and SPECT/CT including, image reconstruction and restoration, kinetic modeling, Alzheimer’s disease (AD) diagnosis, and radiotherapy models. In his earlier work, Dr Knešaurek developed a transformation method for simultaneous Tc-99m/Tl-201 cardiac rest/stress imaging thereby establishing himself as a prominent expert in this field. In 2000, Dr. Knešaurek became involved in cardiac PET imaging with Rb-82 and developed a method of calculating myocardial blood flow and coronary flow reserve. Dr. Knešaurek and his team won SNM 2008 Image of the Year, which was related to minimally invasive treatment of diabetic foot. He has also been involved in development of PET brain imaging, like amyloid and tau imaging, which are related to diagnosing AD and other dementias. Recently, Dr. Knešaurek has been very active in optimizing imaging and dosimetry methods related to Y-90 radiotherapy of unresectable liver cancers, using bremsstrahlung SPECT/CT, PET/CT, and PET/MRI imaging. Dr. Knešaurek has coauthored 3 book chapters, more than 65 peer-reviewed publications, and has presented 30 invited lectures, nationally and internationally.